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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2333c00d57470830622783c8872c37721c10a43c850751bff6c30997bbe2fc73' 
  AND token = 'KFE8W4LIEnc2xZGS0Sm2EwNDwDCyXNkpKlJS1/v9TLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}