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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd2da358d14d35ca69be78d92ac71c446531c3f85776c2825105b9ad64d4f17e8' 
  AND token = 'AcdfZ2TEiP+SUODxzAAUwERSEe5JgTHKSGSvBNW1yzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}