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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b49694b3b3d8bbc9e130d3e2d2570375f32a637615f3d283780b252349ef794b' 
  AND token = '2UMnE60ejHjIcnwjAznRZtOkPev1rZ0GGtFnqrn65Fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}