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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5646c361eb76086d9acb32d216a4ff43c864e94fc8a54ffd50ccc53c860354e2' 
  AND token = 'extEI0CyFHa3Kns4yu1CXCZOwn9+E6iCynUWUCLfFMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}