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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '26daa93494f913c4fdb553e368c0884c21038db0794e44a5ae87d4f06fd55981' 
  AND token = 'M3eiZvOO4uKxPh3WS1+63kDXShuIqh+vfWlbiFw9uNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}