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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1b004d3e22dbca34113c1f72622808a58ae282785aec3f58264010cc3ca04c2c' 
  AND token = 'tJdvZjgY2D1+zVMT31fhdSVYbhcWfEkrPesFbg8JM/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}