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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '557ec65b2e7ca531159ccd8a56ea8ecf6809d9a6497af156f272544c9f09df1b' 
  AND token = 'FfWBtxmv1wTtJXsXLkEiz8k1zXYGRZiz/iQNEC0NzdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}