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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b9456a85094eddf599ee15b179147e4ba759e551000f24955bc2538ebd97eb68' 
  AND token = 'eQ8Psg5sotsA+BMwJI3VcMZPOKswbvUDO20IIYFlv7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}