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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '87a57d5cbdb708578875a0c0781f0d893adc756b40e416df7c417466a2eeadae' 
  AND token = 'ke3pzYXzMF+vK9KU6lufU4U6thLDLRhkBh/5Wj75wkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}