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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7c3cb019e8c1010609a2d2125bb0c88acb37d91a7c4908dc33149be68404fad3' 
  AND token = 'SkEdAdPGQHHAjQ9kuQNR+435MJqGdz0rDdiQVY1H8YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}