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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c482ff59b18260d0ed1f539ad197ad1e2bc9dc198ea880778a580e80a003f47b' 
  AND token = 'xL4YIVmHSL8Rq0i2DeFasM6HMsR3/zhH+5kTXeJXj1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}