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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25f1c04bf9b0988820ba513f0e434c63b7f7b56f2d49b242296077ed199c815b' 
  AND token = '2oe6xrPaHpO2EQwRu3OFDobePx0ipfSAmpIlG/4Y7cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}