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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'be03b1b1e165bb04cbd9b75055d78fc91bd4f92c8226f8f961b2e58330541804' 
  AND token = 'jDr2Imv4gHRtLY/z8aiike4US05e+uchFaHe23XTyto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}