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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '25b91c314cf444e855c3b1eb1ec161e6b682fd7f99c83adf9f1592df6ffd9a50' 
  AND token = 'uDFUkk5E6bbZCxkKcYhRV0wZIyhIuFyeMh1/fgvxvL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}