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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ee906610c33fbae05be4758011987798b1ad41d702ac1ebf2be50a71591af76f' 
  AND token = 'E6Lp6cpS08T+GmJZlMvCdfS3CblMmX3Ur2xt8oE/Bi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}