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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2e8ea045b4b13992e77b4cbebea5311f73994e855d1c3c2be8606d3fbcb29399' 
  AND token = 'B0RQpKkdtgCQBfoc71BtSeM5PE8hRG2T1hW3d907wpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}