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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6c4c8c7554c81c2dfef780f6023beef29f1c1ab748d123557a189e6cc02391cc' 
  AND token = 'kWW/B/Axyt5cbQZIugVR0GNUQiZnuGxHyxAwswOTj4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}