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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b1b7dbb55d59413478c1a07629396192ad39ebb123200cd2e540332e3a1e5311' 
  AND token = 'TqHkfikDMEoOkA86P3/nO4GzBWWnYG1vR+i6huhQOFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}