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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b472cff847c4ce12e48fea249bf421a03a03cb7518afc65857f9a06411c1ca7' 
  AND token = 'Z9B3zzEFh4TUolojy13Ca+o2lF3deODtXuW4N9SbdCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}