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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'adef7ebcb597884192d463425567e019ca33f36d46fafec4c4a8ede7b7179fab' 
  AND token = 'ynCrEmPM+n2YAlizP2U3TGlgk2X0T2iGBT+/m3desQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}