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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '043cc9762d45dedd741a1b139d5f15b777f0489f91c6fa179a45b5244fd1abbc' 
  AND token = 'xt8o3yBdEW17/72n8abAlh9oLNER9zt8ES2PQYltSTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}