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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a6b471a7f42aa089afb6214e3e1378d6c2375d3813a07542f40da573ab50ad06' 
  AND token = 'mN5cgl00tZn3TW30JmfPT8E/GORwBJk+oafL0aNY0LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}