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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5e361fef0b7e37885c067f235d98236c9dcc046010cd987281185b5509d95782' 
  AND token = 'IYY2JmRT1Yx8tSRusDhCI9KrE6pfptrIYVbc4tJQMb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}