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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2fb3d118e7017c4c3a81c5899cc081eb6f755b7c73c5666b2b71063348ff727c' 
  AND token = '2Rfxy71T6XQxLDxpGemSrhBYZmtNl0v+UmaSyPe+sB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}