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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bca2d7a75b7b6c398331d5b264a7b593487f47db5b77a2c41de89e235668e251' 
  AND token = 'OZtp4tX5SSxaeMfo+SN3R3NYPZxfpAwI+gDSU8QIweU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}