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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '666a0c1a03d0613ef3f09a90101a716067d4927b9261fb73e269797ac87e14c6' 
  AND token = 'UHq6TWATELB5u+eru0l/mGmOud5i0kQzPGGUs6AwKd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}