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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ef69efa97ad6e0ce34e83431e2faa4565d405d1f455c66aa1ba05b43110c3159' 
  AND token = 'pLe5DCAhwvHJ/QRoCiNUdVihcRAtzut/f3l/Lt+jqLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}