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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ef5efb1aa2a929625e17a4ab08af8113debc25406d047981cfaa8a51cb492416' 
  AND token = '7Ja7x5FdcFl2B6ZC+QDiGEhY8iDqgqknlaBygdtT72k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}