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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '01cdc1d150d4a435cc1d1917ee65f6117d724948754f354d429a4e207876b758' 
  AND token = 'GmNg5bFddGR5sVNVzOQKcxGaXh6ne+VEsnAjvOSTKjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}