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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ad070d0c9e193b62e55177d1c78acedf89e2a390c6c22b16db79680f506168a2' 
  AND token = '4yuOD4iTaCag+2/PEONKI78A4NFZRDmeAlGsC07VHjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}