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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e5ac2d39c11fecbe7679771ee458d1c120a29b9b31b1209ee9b64a09646e1ebd' 
  AND token = 'sk1f6l5F+q4qZofSb5fxqTPK5dOZwVknTX2r+7vnlqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}