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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0333f47744ae46e257b1571c9f73ea2314ffed414fa5d7a3731379480a86c05b' 
  AND token = 'KAky7gHmz8fGYsMUIsM7C87uE1/U0N5fucVHNIrxDBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}