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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '980735f3fd65b10322aa8d10a145cb6d333ec17b98bf37c17ac48bc3d24f4469' 
  AND token = 'sp6F0Hk3wrFIgRCBlcAMPRZp6JtXA3qkHe9OkTewp0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}