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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'c745b89509af4aba41aabb1ae237a6af4de567b0f8697649b4490b7173d3a781' 
  AND token = 'JZemEV9t8HiIzUL7R10VxT6TQMXO1372avDsqDZai3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}