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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5d7c4d0110f44f2f800126003620d49ebcc930d3994f51075475e09fe5fcabb4' 
  AND token = 'V0y2QUcOaimqnX8NqXbaEyVnQYeD7Bt5c10o5jfzIM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}