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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dd2d905d9b908e12c0e06d3c187d15643f7214c04941488dacc140bca55f5926' 
  AND token = 'IbpfYO/XjnI1dppddHq/DhCSr0qecHiDuRdSsarxVeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}