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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '50c01f192014c63f66b29949db723144a36cc2254c97b1a965a29d063e2fc3b1' 
  AND token = 'yiNeekxIiIoB0auQKnaQHC2SJdRi2F1l+yGoQ6y1Bw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}