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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6a1c81caf31e1ccbdcf27cd2913f9452edaed3d9642789446b71616209254b44' 
  AND token = '/62GIsDKJXi6o3uarvNQRkEFp50MbLWN8Tn0xKIVqWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}