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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a26a2dab172e2fa12a023006fd36040a95daec98d56f6ea6e41a10d7cfda846d' 
  AND token = 'aWmhLFxXTEU3XodB9yGzZnpUlUeVATWnFgqBvlhnXwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}