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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6d10b42301af9b6ebbe24f034582bc764b79c3600424dbd01773fffe3d0e7d07' 
  AND token = 'fll3H/hS4Cf883RgOtMCm9FF6/cyvxFA4lWtMl5pc84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}