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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'fe16bcef804311f2f1f1607292d3a3dfbcfa59d7a821ce4f276c25073e11f88f' 
  AND token = 'Bi1qveKStjBWIOTnHubMX3EERuNFyQOiGLfQVOVTagI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}