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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bd7b8cb5d0bf29ec148351b62d069656a10711ded14e513c8425cdde598aa29f' 
  AND token = 'Kn04UMspxdwwdbG3iqm5z6jHTjiEdzNIYcukdDQ6ZjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}