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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4a5b193e1c35df69d4e91b650a13d51da22f19872045c8c97accc0bf95b88d53' 
  AND token = 'w+e6f6X6wYd9XQYekVX7X1WUA/LrhUc+mcW2CzRln2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}