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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9b6819981870b56fa8d199d1a8a60f8d3586d6ad024f73d1e075f6f29215a6f3' 
  AND token = 'OXLOkGJlDnvlLTR64aEznZpB/NCd1LepE36Ac0AuapM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}