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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'e81738d71748de0135a8ea3ac2870e349b45f5413bc757ee2206c39eeb3dbc45' 
  AND token = 'QITxZS9ZJT0P8D3cD8MmyagxWc71Ua2RGacG23Ts+a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}