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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '912790891e8b8262202caeb42cc903fc52ef6fb3683553eca34df35ce91343f8' 
  AND token = 'NlZ+eMkbjdY4nNbhtHKXu92VxWFLgMkk8AWeaWhzYq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}