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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7080a218b8d05053e1dc2b04325078e665c5cffcf76f6710deeb842c930c5551' 
  AND token = 'AGn4U1NBLo5eVadcWW6RWy0jZO2L0M2owhlTBHekp+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}