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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4311ccaddfecc05bd6694313e64244561d32e411c1bb1ea88167f5db1a13d8aa' 
  AND token = 'uuqo3XaD9mzMWFdqNK50IYyvVXB1Mz4fkBq0g9abRsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}