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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '407075caf1d80dca8e9bd86a3812b05e0180ccb406fb9c20638b381de32177d0' 
  AND token = 'rVaad8RhuKZNOUah7upIFalBGRSYwGfAc+Wde7RXi3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}