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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0d34e0acede66fe5488ded89d4a5aa1d765d9e81411260f77c45a27e5add1222' 
  AND token = '3WaUr2/JNXIHm27HHxGudRdpsl1RfZc1qlORLNKtwQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}